Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Processes of preparing a desired or intentional composition...
Patent
1987-08-28
1989-02-14
Kight, John
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
Processes of preparing a desired or intentional composition...
528 54, 528 55, 528 81, 528 83, 528905, C08G 1830
Patent
active
048046914
ABSTRACT:
A method for making an adhesive for use in joining soft living tissue including the steps of preparing a hydroxyl-terminated polyester by reacting a biodegradable monomer with a polyhydroxy polymerization initiator in the presence of an amount up to about 2.0 weight percent of a catalyst, and then preparing a diisocyanate-terminated prepolymer adhesive by reacting about 24 to 92 weight percent of the hydroxy-terminated polyester with about 8 to 76 weight percent excess aromatic diisocyante. The polyester and the diisocyanate are preferably dissolved in an organic solvent prior to the mixture thereof in a ratio of solids to solvent of about 60:40. The polyester is a polymer or copolymer of lactide, glycolide or .epsilon.-caprolactone. The initiator is ethylene glycol, diethylene glycol, pentaerythritol or 1,1,1-tris (hydroxymethyl) ethane. The catalyst is stannous octoate, a zinc compound, an aliphatic tertiary amine, dibutyltin diacetate or 1,4-diazabicyclo [2,2,2] octane.
REFERENCES:
patent: 3221745 (1965-12-01), Coover, Jr. et al.
patent: 3463158 (1969-08-01), Schmitt et al.
patent: 3867190 (1975-02-01), Schmitt et al.
patent: 4057535 (1977-11-01), Lipatova et al.
patent: 4243775 (1981-01-01), Rosensaft et al.
patent: 4273920 (1981-06-01), Nevin
patent: 4539981 (1985-09-01), Tunc
patent: 4595713 (1986-06-01), St. John
Stephen C. Weber, MD, and Michael W. Chapman, MD, "Adhesives in Orthopaedic Surgery", Clinical Orthopaedics and Related Research, No. 191, Dec., 1984.
Karl H. Siedentop, MD, David M. Harris, PhD, and Ben Sanchez, MD, "Autologous Fibrin Tissue Adhesive", Laryngoscope 95, Sep. 1985.
Karl H. Siedentop, MD, David M. Harris, PhD, and Dennis F. Weber, D.D.S., "Fibrin Tissue Adhesive and Glass Ceramic Strut for Ossicular Chain Replacement", The American Journal of Otology, Vol. 6, No. 3, May, 1985.
Marvin H. Meyers, MD, and Michael Herron, D.V.M., "A Fibrin Adhesive Seal for Repair of Osteochondral Fracture Fragments", Clinical Orthopaedics and Related Research, No. 182, Jan.-Feb., 1984.
Michael Evan Sachs, MD, "Enbucrilate as Cartilage Adhesive in Augmentation Rhinoplasty", Arch Olotaryngol, vol. 111, Jun. 1985.
"Human Super Glue Cited for Microperforations", Ocular Surgery News, Jul. 15, 1985, author unknown.
Max L. Ronis, MD, John D. Harwick, MD, Romona Fung, MD, and Michael Dellavecchia, MD, "Review of Cyanoacrylate Tissue Glues with Emphasis on Their Otorhinolaryngological Applications", Laryngoscope 94, Feb. 1984.
M. C. Harper, "Viscous Isoamyl 2-Cyanoacrylate as an Osseous Adhesive in the Repair of Osteochondral Fractures", Orthopaedic Research Society, 1985.
Dunn Richard L.
English James P.
McNeely Gerald W.
Acquah Sam A.
Kight John
Richards Medical Company
LandOfFree
Method for making a biodegradable adhesive for soft living tissu does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for making a biodegradable adhesive for soft living tissu, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for making a biodegradable adhesive for soft living tissu will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1366058