Method for magnetically separating cells into fractionated flow

Details Method for magnetically separating cells into fractionated flow Method for magnetically separating cells into fractionated flow

1997-02-26

1999-10-19

Weber, Jon P.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

4351734, 435 2, 209214, 209216, 2092231, 209231, 209543, 209695, 210223, 210695, C12N 500, C12N 1300, A01N 102, B03C 100, B07C 502, B07C 900, B01D 3506

Patent

active

059688203

ABSTRACT:
A method for separating cells is presented. The method provides a flow through fractional cell sorting process that is based on the application of a magnetic force to cells having a range of magnetic labeling densities. Magnetically labeled cells are introduced into a flow channel. The cells are continuously fractionated into flow streams based on magnetic susceptibility by subjecting the cells in the flow channel to a magnetic field. The fractionated cells are recovered based on their response to the magnetic field. Methods employing dipole fractional sorters and quadrapole annular sorters are also presented.

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