Method for macerating biological material and apparatus for...

Details Method for macerating biological material and apparatus for... Method for macerating biological material and apparatus for...

2007-02-22

2011-11-29

Lankford, Leon B (Department: 1651)

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Cell membrane or cell surface is target

C435S173400, C435S173700

Reexamination Certificate

active

08067216

ABSTRACT:
In order to ensure consistently good maceration of biological material in an electroporation reactor, it is proposed to monitor the conductivity of the mixture therein and to detect any arcing which occurs therein. The results of such monitoring are used to modify the operating voltage of the electroporation reactor and/or the composition of the mixture located in the reactor channel.

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patent: 6074605 (2000-06-01), Meserol et al.
patent: 2002/0137121 (2002-09-01), Rubinsky et al.
patent: 2003/0011386 (2003-01-01), Xie et al.
patent: 2004/0084381 (2004-05-01), Korenev
patent: 10144486 (2003-04-01), None
H. Bluhm, W. Frey, C. Gusbeth, M. Sack and C. Schultheiss, IHM, “Aufschluss und Abtötung biologischer Zellen mit Hilfe starker gepulster elektrischer Felder” in Nachrichten des Forschungszentrums Karlsruhe, vol. 35, issue 3, 2003, pp. 105 to 100.

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