Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1998-12-17
1999-10-26
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514 79, 558 81, 544 1, C07F 9547, C07F 9576
Patent
active
059729120
ABSTRACT:
A method of lyophilizing an oxazaphosphorin and a preparation produced thereby including dissolving an oxazaphosphorin in water, adding an amino acid to a molar ratio of between 1 to 10 amino acid to 1 oxazaphosphorin to produce a mixture and lyophilizing said mixture to remove said water, is disclosed.
REFERENCES:
patent: 3732340 (1973-05-01), Arnold et al.
patent: 4537883 (1985-08-01), Alexander et al.
patent: 4777043 (1988-10-01), Bennett et al.
patent: 4882452 (1989-11-01), Engel et al.
patent: 5204335 (1993-04-01), Sauerbier et al.
patent: 5227373 (1993-07-01), Alexander et al.
Effects of Excipients on the Crystallization of Pharmaceutical Compounds During Lyophilization, Korey, D.J., J. Parenter. Science Technology, 43, 2 (1989).
Characterization of the Sucrose/Glycine/Water System by Differential Scanning Calorimetry and Freeze-Drying Microscope, Kasraian, K., et al., Pharaceutical Development and Technology 3(2) 233-239 (1988).
Kovalcik Thomas R.
Marek Michael J.
Smith Garnet G.
Perez Daniel F.
S.P. Pharmaceuticals
Shah Mukund J.
Sripada Pavanaram K
LandOfFree
Method for lyophilizing ifosfamide does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for lyophilizing ifosfamide, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for lyophilizing ifosfamide will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-764659