Method for lowering cholesterol employing a phosphonomethylphosp

Details Method for lowering cholesterol employing a phosphonomethylphosp Method for lowering cholesterol employing a phosphonomethylphosp

1992-06-11

1995-06-27

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514107, 514108, A61K 3166

Patent

active

054280281

ABSTRACT:
A method is provided for inhibiting cholesterol biosynthesis by inhibiting de novo squalene production employing methylene phosphonoalkylphosphinate compounds.

REFERENCES:
patent: 4371527 (1983-02-01), Bentzen
patent: 4871721 (1989-10-01), Biller
patent: 4924024 (1990-05-01), Biller
patent: 5157027 (1992-10-01), Biller
Kramsch et al. Science 213;1511-1512 Sep. 25, 1981.

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