Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1992-01-27
1993-07-27
Robinson, Allen J.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
436173, 436806, 1286534, 514 12, 514836, 424 11, G01N 2408, A61K 3700
Patent
active
052308839
ABSTRACT:
Improved methods of selectively localizing, imaging and/or treating tumors, which have a net negative charge, employ novel compositions containing non-immunogenic complexes having a net positive charge in a sterile solution. The complexes contain polylysine, a linking agent bound to less than all of the lysyl groups of the polylysine, and an imaging agent or a chemotherapeutic agent which is also bound to the linking agent.
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Kornguth Steven
Nickles Robert J.
Robins H. Ian
Turski Patrick
Hollinden Gary E.
Robinson Allen J.
Wisconsin Alumni Research Foundation
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