Method for loading sample supports for mass spectrometers

Details Method for loading sample supports for mass spectrometers Method for loading sample supports for mass spectrometers

1997-07-10

1998-06-23

Nguyen, Kiet T.

Radiant energy

Ionic separation or analysis

With sample supply means

H01J 4900

Patent

active

057708606

ABSTRACT:
A method for rapid loading of large sample supports with a very large number of analyte samples for mass spectrometric analysis using the ionization method of matrix-assisted desorption by laser bombardment (MALDI). The method consists of using microtiter plates already introduced in biochemistry and molecular genetics for parallel processing of a large number of dissolved samples and a multiple pipette unit for simultaneous transfer of sample solution quantities from all reaction wells on a microtiter plate to the sample support, the sample support having at least the same size. By repeated loading with samples from other microtiter plates, spaced between the samples already applied, a very high density of samples can be achieved. Some of these samples can be reserved for a mass spectrometric determination of the sample positioning on the sample support, and the positions of the other samples can then be interpolated.

REFERENCES:
patent: 4919894 (1990-04-01), Daniel
patent: 5288644 (1994-02-01), Beavis et al.
patent: 5498545 (1996-03-01), Vestal

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