Method for laser desorption mass spectrometry using porous...

Chemistry: analytical and immunological testing – Nuclear magnetic resonance – electron spin resonance or other...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07462494

ABSTRACT:
Articles and methods for the high-energy desorption/ionization of various compositions are disclosed. Methods of the invention utilize porous substrates, optionally in combination with one or more surface coatings and fillers, to provide enhanced desorption of analytes. Such enhanced desorption is particularly useful in fields of analysis such as mass spectrometry. This enhanced desorption has various utilities. For example, use of the porous substrate may allow desorption to be performed without the use of chemical matrices.

REFERENCES:
patent: 3383247 (1968-05-01), Adlhart et al.
patent: 4539256 (1985-09-01), Shipman
patent: 5130342 (1992-07-01), McAllister et al.
patent: 5385694 (1995-01-01), Wu et al.
patent: 5696198 (1997-12-01), Chereisky et al.
patent: 5945175 (1999-08-01), Yahiaoui et al.
patent: 6010776 (2000-01-01), Exsted et al.
patent: 6096213 (2000-08-01), Radovanovic et al.
patent: 6265068 (2001-07-01), David et al.
patent: 6288390 (2001-09-01), Siuzdak et al.
patent: 2002/0171037 (2002-11-01), Ellson et al.
patent: 2003/0218130 (2003-11-01), Boschetti et al.
patent: 2004/0094705 (2004-05-01), Wood et al.
patent: 0542522 (1993-05-01), None
patent: WO 89/11608 (1989-11-01), None
patent: WO 92/02580 (1992-02-01), None
patent: WO 01/66820 (2001-09-01), None
patent: WO 03/025631 (2003-03-01), None
patent: WO 03/051498 (2003-06-01), None
patent: WO 03/075307 (2003-09-01), None
Wei et al. “Desoprtion-ionization mass spectrometry on porous silicon”, Nature, 1999, v. 399, pp. 243-246.
Worrall et al. “Purification of contaminated peptides and proteins on synthetic membrane surfaces for MALDI”, Anal Chem., 1998, v. 70, pp. 750-756.
Sun et al. “Preparation of high density polyetheylene hollow fiber membranes by thermally induced separation method”, Koubunshironbunshu, 1998, v. 55, No. 7, pp. 378-384, Abstract; http://www.aist.go.jp/NIMC/publication/annual98/13/13—8.html.
Blackledge et al. “Polyethylene membrane as a sample support for direct MALDI analysis of high mass proteins”, Anal. Chem., 1995, v. 67, pp. 843-848.
McComb et al. “Application of nonporous polyurethane (PU) membranes and porous PU thin films as sample supports for MALDI-MS of wheat proteins”, Can. J. Chem., 2001, v. 79, pp. 437-447.
Wei et al, “Desorption-ionization mass spectrometry on porous silicon”, Letters to Nature, v. 399, p. 243-246, (1999).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for laser desorption mass spectrometry using porous... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for laser desorption mass spectrometry using porous..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for laser desorption mass spectrometry using porous... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4027921

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.