Method for labelling leucocytes with indium in-111 oxine

Details Method for labelling leucocytes with indium in-111 oxine Method for labelling leucocytes with indium in-111 oxine

1989-08-17

1992-03-03

Maples, John S.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

530380, 530402, A61K 39395

Patent

active

050931040

ABSTRACT:
An improved method for radio-labelling leucocytes in vitro with Indium In-111 oxide (Indium In-111 oxyquinoline) for use in scintigraphic imaging of inflammatory lesions and abscesses enhances the leucocyte specific labelling efficiency by depleting residual RBCs from the leucocytes prior to labelling. The RBCs are depleted from the leucocytes by means of a rocking step.

REFERENCES:
H. J. Danpure et al., Nuclear Medicine Communications (1988), vol. 9, pp. 681-685.
Operating Instructions for a "Hema Tek" Aliquot Mixer from Miles Laboratories, Inc.

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