Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Reexamination Certificate
2008-05-27
2008-05-27
Hutson, Richard (Department: 1656)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
C435S106000
Reexamination Certificate
active
10508728
ABSTRACT:
A method for producing L-threonine using a microorganism is provided. In the method, the threonine dehydratase (tdc) gene existing in the genomic DNA of the microorganism is partially deactivated using a recombination technique. For a microorganism strain with enhanced activity of threonine operon-containing enzymes and the phosphoenolpyruvate carboxylase (ppc) gene, the tdc gene engaged in one of the four threonine metabolic pathways is specifically deactivated, thereby markedly increasing the yield of L-threonine.
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Cho Jae Yong
Kim Dae Cheol
Lee Byoung Choon
Lee Jin Ho
Park Jae Yong
Cheil Jedang Corporation
Hutson Richard
Lee Jae Wan
Rothwell, Figg Ernst & Manbeck, PC
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