Method for killing gram positive bacteria with isolated type II

Details Method for killing gram positive bacteria with isolated type II Method for killing gram positive bacteria with isolated type II

1996-07-19

1999-02-23

Naff, David M.

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

424 941, 514 2, 514 21, 435183, 435195, 435198, 4352521, 4352525, 4352527, 4352529, 4352531, 4352532, 4352534, A61K 3846, C12N 920

Patent

active

058740791

ABSTRACT:
Disclosed herein are methods for killing Gram-positive bacterial infections in animals comprising exposing the bacteria to Gram-positive bactericidal-effective amounts of Type II phospholipase A2. The Type II phospholipase A2 can be isolated from mammalian species including humans, cows, rabbits, rats, mice, cats, and dogs. Type II phospholipase A2 is effective in treating infections in mammals, including humans, caused by gram-positive bacteria such as Staphylococcus aureus. Also disclosed are pharmaceutical formulations for use in the methods.

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