Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2005-04-05
2005-04-05
Horlick, Kenneth R. (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091100, C536S023100, C536S024300, C536S024330, C536S025300
Reexamination Certificate
active
06875568
ABSTRACT:
The invention generally concerns the use of amino acid denaturants for denaturing or separating double stranded nucleic acid molecules. More specifically, the present invention provides a method for the rapid isolation and recovery of a desired target DNA or RNA molecules from a mixture or library containing such molecules. The method involves the use of haptenylated probes and amino acid denaturants to select the desired molecules and eliminate the undesired library members from a sample. The invention also provides a method in which larger or full-length nucleic acid molecules can be isolated from the subpopulation of desired molecules.
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Mytelka, D.S. and Chamberli
Jesse Joel
Li Wu-bo
Nisson Paul E.
Horlick Kenneth R.
Invitrogen Corporation
Lu Frank
Sterne Kessler Goldstein & Fox P.L.L.C.
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