Method for introducing and expressing genes in animal cells, and

Details Method for introducing and expressing genes in animal cells, and Method for introducing and expressing genes in animal cells, and

1998-07-30

2000-11-21

Chambers, Jasemine

Chemistry: molecular biology and microbiology

Process of mutation, cell fusion, or genetic modification

Introduction of a polynucleotide molecule into or...

435455, 435472, 435480, 435 691, 4353201, 514 44, 4241841, 424 931, 424 9321, 424 934, C12N 1563, C12N 1500, C12N 500, A01N 4304, A61K 3170

Patent

active

061501700

ABSTRACT:
A method for introducing and expressing genes in animal cells is disclosed comprising infecting said animal cells with live invasive bacteria, wherein said bacteria contain a eukaryotic expression cassette encoding said gene. The gene may encode, e.g., a vaccine antigen, an therapeutic agent, an immunoregulatory agent or a anti-sense RNA or a catalytic RNA.

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