Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2006-10-24
2006-10-24
Nguyen, Dave Trong (Department: 1633)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S069100, C435S320100, C424S450000
Reexamination Certificate
active
07125718
ABSTRACT:
A method for introducing and expressing genes in animal cells, in which the animal cells are transfected with bacterial blebs containing a eukaryotic expression cassette encoding the gene. Bacterial blebs comprising a eukaryotic expression cassette, wherein the bacterial blebs are derived from gram negative bacteria.
REFERENCES:
patent: 5985880 (1999-11-01), Chang et al.
patent: WO 93/22443 (1993-11-01), None
patent: WO 93/23534 (1993-11-01), None
Mooij P, Heeney JL, Rational development of prophylactic HIV vaccines based on structural and regulatory proteins, 2002, Vaccine 20:304-321.
Sadelain M, Insertional oncogenesis in gene therapy: how much of a risk? 2004, Gene Therapy 11:569-573.
Griesenbach U, Geddes DM, Alton EWFW, Gene therapy for cystic fibrosis: an example for lung gene therapy, 2004, Gene Therapy 11:S43-S50.
Nanni P, Forni G, Lollini P-L, Cytokine gene therapy: hopes and pitfalls, 1999, Ann. Oncol. 10:261-266.
Branch AD, A good antisense molecule is hard to find, 1998, trends Biochem. Sci. 23:45-50.
Green DW, Roh H, Pippin J, Drebin JA, Antisense oligonucleotides: an evolving technology for the modulation of gene expression in human disease, 2000, J. Am. Coll. Surg. 191:93-105.
Jen K-Y, Gewirtz AM, Suppression of gene expression by targeted disruption of messenger RNA: available options and current strategies, 2000, Stem Cells 18:307-319.
Crooke ST, Basic principles of antisense therapeutics, 1998, from Antisense Research and Application, Chapter 1, Springer-Verlag, New York, pp. 1-50.
Sioud M, Nucleic acid enzymes as a novel generation of anti-gene agents, 2001, Curr. Mol. Med. 1:575-588.
Abbas AK, Lichtman AH, Pober JS, Cellular and Molecular Immunology 2nded. 1994, W.B. Sanunders Company, Philadeplphia, pp. 245 and 321.
Kadurugamuwa JL, Beveridge TJ, Delivery of the non-membrane-permeative antibiotic gentamycin into mammalian cells by usingShigella flexnerimembrane vesicles, 1998, Antimicrob Agents Chemother 42: 1476-1483.
Al-Hendy, Ayman, et al.; Lipopolysaccharide O Side Chain ofYersinia enterocoliticaO:3 Is an Essential Virulence Factor in an Orally Infected Murine Model; Infection and Immunity; Mar. 1992; vol. 60, No. 3, pp. 870-875; American Society for Microbiology; USA.
Altman, Sidney; Commentary—RNA enzyme gene therapy; Proc. Natl. Acad. Sci; Dec. 1993; vol. 90, pp. 10898-10900; Department of Biology, Yale University, New Haven, CT.
Archambault, Jacques, et al.; Genetics of Eukaryotic RNA Polymerases I, II, and III; Microbiological Reviews; Sep. 1993, vol. 57, No. 3, pp. 703-724; American Society for Microbiology.
Formal, S. B., et al.; Construction of a Potential Bivalent Vaccine Strain: Introduction ofShigella sonneiForm I Antigen Genes into thegalE Salmonella typhiTy21a Typhoid Vaccine Strain; Infection and Immunity; Dec. 1981; vol. 3, pp. 746-750; Division of Communicable Disease and Immunology, Walter Reed Army Institute of Research.
Beato, Miguel; Transcriptional control by nuclear receptors; The FASEB Journal; Apr. 1991; vol. 5, pp. 2044-2051; Institut für Molekularbiologie und Tumorforschung, I.M.T.
Braun, Stephen E., et al.; Metabolic correction and cross-correction of mucopolysaccharidosis type II (Hunter syndrome) by retroviral-mediated gene transfer and expression of human iduronate-2-sulfatase; Proc. Natl. Acad. Sci. USA; Dec. 1993; vol. 90, pp. 11830-11834; Medical Sciences.
Brundage, Rodney A., et al.; Expression and phosphorylation of theListeria monocytogenesActA protein in mammalian cells; Proc. Natl. Acad. Sci. USA; Dec. 1993, vol. 90, pp. 11890-11894.
Buchmeier, Nancy A., et al.; Recombination-deficient mutants ofSalmonella typhimuriumare avirulent and sensitive to the oxidative burst of macrophages; Molecular Microbiology, 1993, vol. 7, No. 6, pp. 933-936.
Bushman, Frederick D.; Tethering human immunodeficiency virus 1 integrase to a DNA site directs integration to nearby sequences; Proc. Natl. Acad. Sci. USA; Sep. 1994, vol. 91, pp. 9233-9237; Salk Institute for Biological Studies, La Jolla, California.
Chilton, Mary-Dell; Agrobacterium gene transfer: Progress on a “poor man's vector” for maize, Commentary; Proc. Natl. Acad. Sci USA; Apr. 1993, vol. 90, pp. 3119-3120; Ciba-Geigy Corporation, Research Triangle Park, North Carolina.
Curtiss, III, Roy, et al.;Salmonella typhimuriumDeletion Mutants Lacking Adenylate Cyclase and Cyclic AMP Receptor Protein Are Avirulent and Immunogenic; Infection and Immunity, Dec. 1987, vol. 55, No. 12, pp. 3035-3043; American Society for Microbiology.
Dargis, M.; Modification in Penicillan-Binding Proteins during In Vivo Development of Genetic Competence ofHaemophilus influenzaeIs Associated with a Rapid Change in the Physiological State of Cells; Infection and Immunity; Oct. 1992, vol. 60, No. 10, pp. 4024-4031; American Society for Microbiology.
d'Hauteville, Hélène, et al., Phosphorylation of IcsA by cAMP-dependent protein kinase and its effect on intercellular spread ofShigella flexneri; Molecular Microbiology; 1992, vol. 6, No. 7, pp. 833-841; Unité de Pathogénie Microbienne Moléculaire et Unité 199.
Doggett, Teresa A., et al., Immune Responses toStreptococcus sobrinusSurface Protein Antigen A Expressed by RecombinantSalmonella typhimurium; Infection and Immunity; May 1993, vol. 61, No. 5, pp. 1859-1866; American Society for Microbiology.
Dreiseikelmann, Brigitte; Translocation of DNA across Bacterial Membranes; Microbiological Reviews; Sep. 1994, vol. 58, No. 3, pp. 293-316; Mikrobiologie/Gentechnologie, Universität Bielefeld, Bielefeld Germany.
Elsinghorst, Eric A.; Molecular Cloning of Epithelial Cell Invasion Determinants from EnterotoxigenicEscherichia coli; Invection and Immunity; Jun. 1992, vol. 60, No. 6, pp. 2409-2417; Department of Bacterial Immunology, Washington, DC.
Flynn, J. L., et al.; Generation of a cytotoxic T-lymphocyte response using aSalmonellaantigen-delivery system; Molecular Microbiology; 1990, vol. 4, No. 12, pp. 2111-2118; Department of Molecular Biology, Research Institute of Scripps Clinic, La Jolla, California.
Fynan, Ellen F., et al.; DNA vaccines: Protective immunizations by parenteral, mucosal, and gene-gun inoculations; Proc. Natl. Acad. Sci. USA; Dec. 1993, vol. 90, pp. 11478-11482; Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts.
Galán, Jorge E., et al.; Expression ofSalmonella typhimuriumGenes Required for Invasion Is Regulated by Changes in DNA Supercoiling; Infection and Immunity; Jun. 1990, pp. 1879-1885; Department of Biology; Washington University, St. Louis, Missouri.
Gao, Xiao-Ming, et al.; RecombinantSalmonella typhimuriumStrains That Invade Nonphagocytic Cells Are Resistant to Recognition by Antigen-Specific Cytotoxic T Lymphocytes; Infection and Immunity; Sep. 1992, vol. 60, No. 9, pp. 3780-3789; Institute of Molecular Medicine and Nuffield Department of Pathology, John Radcliffe Hospital, Oxford and The Wellcome Research Laboratories, Beckenham, Kent, UK.
Goodman, Stacey, et al.; Recombinant Adeno-Associated Virus Mediated Gene Transfer Into Hematopoietic Progenitor Cells; Blood; Sep. 1994, vol. 84, No. 5, pp. 1492-1500; The American Society of Hematology.
Harborne, Nerina R., et al.; Transcriptional control, translation and function of the products of the five open reading frames of theEscherichia coli niroperon; Molecular Microbiology; 1992, vol. 6, No. 19, pp. 2805-2813; School of Biochemistry, University of Birmingham, Birmingham, UK.
Holloway, B.W., et al.; Genetics for all bacteria; Annual Review of Microbiology, Article 23, Annual 1993, vol. 47, pp. 659-685; North Carolina Libraries for Virtual Education (NCLIVE).
Ishihama, Akira; Role of the RNA polymerase a subunit in transcription activation; Molecular Microbiology; 1992, vol. 6, No. 22, pp. 3283-3288; Department of Molecular Genetics, National Institute of Genetics, Mishima, Shizuoka, Japan.
Kerppola, Tom K., et al.; RNA polymerase: regulation of transcript elongation and termination; The FASEB Journal; Oct. 1991, vol. 5, pp. 2833-2842; Division of Biochemistry and Molecular Bi
Hone David
Powell Robert J.
Hultquist Steven J.
Intellectual Property / Technology Law
Nguyen Dave Trong
Riggins Patrick S.
University of Maryland Biotechnology Institute
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