Method for inhibition of erythrocyte aggregation using anellated

Details Method for inhibition of erythrocyte aggregation using anellated Method for inhibition of erythrocyte aggregation using anellated

1988-11-30

1991-01-01

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514183, 5142268, 5142282, 5142285, 5142288, 5142328, 514241, 514242, 514247, 514255, 514256, 514269, 514338, 514361, 514362, 514363, 514375, 514366, 514378, 514381, 514386, 514397, A61K 31415, A61K 3154, A61K 31535, A61K 3153, A61K 3150, A61K 31495, A61K 31505, A61K 3144, A61K 3141, A61K 31425, A61K 3142

Patent

active

049818643

ABSTRACT:
The present invention is concerned with the use of compounds of the general formula: ##STR1## wherein R.sub.1 is a phenyl radical of the general formula: ##STR2## or R.sub.1 is a 5 or 6 membered heterocycle or when X is a valency bond R.sub.1 is also H, OH, mercapto, amino, alkyl, alkenyl, alkynyl, haloalkyl, alkylthio, formylaminoalkyl, pyridylcarbonylamino, cycloalkyl, or cycloalkenyl, alkoxyalkyl, carboxyalkyl, alkoxycarbonylalkyl or hydroxyalkyl of claim 1 or 2 for the preparation of pharmaceutical compositions with an erythrocyte aggregation inhibition action useful, for example, in states of shock or circulatory disturbance.

REFERENCES:
patent: 4666923 (1987-05-01), Holck et al.
patent: 4695567 (1987-09-01), Mertens et al.
patent: 4710510 (1987-12-01), Mertens et al.
patent: 4730003 (1988-03-01), von der Saal et al.
patent: 4810801 (1989-03-01), Mertens et al.
patent: 4831032 (1989-05-01), von der Saal et al.
patent: 4874756 (1989-10-01), Mertens et al.
Chemical Abstracts, vol. 106: 213949k (1987).

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