Method for inhibiting vasoconstriction

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31435

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active

056913478

ABSTRACT:
The bicyclic derivatives of pyridines of the formula ##STR1## and their non-toxic, pharmaceutically acceptable salts and a process and intermediates for their preparation which compounds are inhibitors of angiotensin II effects, particularly a vasoconstrictor activity.

REFERENCES:
patent: 4559402 (1985-12-01), Irikura et al.
patent: 5420138 (1995-05-01), Corbier et al.
Awano et al. I, Chem. Pharm. Bull., 34(7), 2833-39 (1986).
Awano et al. II, Chem. Pharm. Bull., 34(7), 2828-32 (1986).

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