Method for inhibiting the dissolution of antiperspirant compound

Details Method for inhibiting the dissolution of antiperspirant compound Method for inhibiting the dissolution of antiperspirant compound

1993-04-26

1997-10-14

Dodson, Shelley A.

Drug, bio-affecting and body treating compositions

Anti-perspirants or perspiration deodorants

424 47, 424 66, 424 67, 424 68, A61K 732, A61K 734, A61K 736, A61K 738

Patent

active

056769369

ABSTRACT:
A method of inhibiting the dissolution in anhydrous ethanol or isopropanol of a powdered aluminium-containing basic halide antiperspirant agent which comprises incorporating in the ethanol or isopropanol an amount effective to inhibit said dissolution of an alcohol soluble or alcohol-insoluble dissolution-inhibiting compound selected from the group consisting of compounds having a basic nitrogen function and compounds having a basic oxygen function. Examples of dissolution-inhibiting compounds are urea, thiorea, amino acids, C.sub.1 -C.sub.20 alkylamines and hydroxyalklyamines, inorganic bases, and alkali metal and alkaline-earth metal salts of inorganic acids and C.sub.1 -C.sub.20 organic carboxylic acids. The dissolution-inhibiting compound may alternatively be a particulate alcohol-insoluble inorganic drying agent such as a molecular sieve.

REFERENCES:
patent: 2736683 (1956-02-01), Apperson et al.
patent: 3792068 (1974-02-01), Luedders et al.
patent: 3932609 (1976-01-01), Rosenstreich et al.
patent: 4108977 (1978-08-01), Kenkare et al.
The Journal of Investigative Dermartology, 1954, vol. 23, No. 6, pp. 411 to 422.

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