Method for inhibiting production of toxins from enteropathogenic

Details Method for inhibiting production of toxins from enteropathogenic Method for inhibiting production of toxins from enteropathogenic

1998-06-26

2000-08-08

Witz, Jean C.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Bacteria or actinomycetales

C12N 120

Patent

active

060998334

ABSTRACT:
A method of treating a human infected with enteropathogenic Escherichia coli which produces toxins, by administering to the human a butyric-acid bacteria and an antibiotic, such as fosfomycin.

REFERENCES:
Tsuyoshi Ushijima, "Semisynthetic Media for In Vitro Examination of the Contributions of Nutrients and Growth Inhibitors for Symbiosis or Antagonism of the Bacteria in Ileum, Caecum and Colon of the Mammalian", Medical and Biology, 106, No. 4, 199-204 (1983).
Takashi Shimoyama et al., "Intestinal Bacterial Flora and Disease: Mainly on Large Intestine Disease", Most Up-to-Date Medical, 33(10), 2047-2055 (1978).
Tsuyoshi Ushijima, "A Simple Anaerobic Continuous Culture System for the Study of Bacterial Symbiosis and Antagonism", Medical and Biology, 108, No. 2, 71-74 (1984).
T. Ushijima and A. Seto, Selected Faecal Bacteria and Nutrients Essential for Antagonism of Salmonella typhimurium in Anaerobic Continuous Flow cultures, J. Med. Microbiol., 35, 111-117 (1983).
Tsuyoshi Ushijima, "Difference of Antagonistic Effects of Resident Colonic Bacteria for Enterohemorrhagic Escherichia Coli in AnaerobicContinuous Flow Cultures Using Mimic Media of Colonic Contents of Adult and Breast-fed New Born", Medical and Biology, 134, No. 5, 149-154 (1997).
Tsuyoshi Ushijima, "Potent Growth Inhibition of Enterohemorragic Escherichia coli Some Other Gram Negative Enteropathogens by Resident Escherichia coli Grew maximum Level in Anaerobic Cultures",Medical and Biology, 134, No. 2, 39-44 (1997).
Tsuyoshi Ushijima, "Potent Antagonistic Effect of Resident Escherichia coli in Human Colon on Enteropathogenic and Enterohemorragic Escherichia coli", Medical and Biology, 127, No. 1, 5-9 (1993).
Tsuyoshi Ushijima, "Antagonistic Effects of Human Colonic Bacteria on Some Enteropathogenic Escherichia coli", Medical and Biology, 126, No. 1, 9-14 (1993).

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