Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-01-26
1990-06-26
Nutter, Nathan M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514576, 424 78, A61K 3174
Patent
active
049372548
ABSTRACT:
Postsurgical adhesion formation is inhibited by the topical administration to the site of surgical trauma of a non-steroidal anti-inflammatory drug, preferably ibuprofen, suprofen, or tolmetin.
REFERENCES:
patent: 3755558 (1973-08-01), Scribner
patent: 4141973 (1979-02-01), Balazs
patent: 4166800 (1979-09-01), Fong
patent: 4240163 (1980-12-01), Galin
patent: 4337251 (1982-06-01), Pfirrmann
patent: 4346108 (1982-08-01), Singer
patent: 4389330 (1983-06-01), Tice et al.
patent: 4427649 (1984-01-01), Dingle et al.
patent: 4474751 (1984-10-01), Haslam et al.
patent: 4474752 (1984-10-01), Haslam et al.
patent: 4474753 (1984-10-01), Haslam et al.
patent: 4478822 (1984-10-01), Haslam et al.
patent: 4485088 (1984-11-01), Chvapil
patent: 4517295 (1985-05-01), Bracket et al.
patent: 4522803 (1985-06-01), Lenk et al.
Stangel et al., "Formation and Prevention of Postoperative Abdominal Adhesions", J. of Repro. Med., vol. 29, No. 3, Mar., 1984, pp. 143-156.
"The Cause and Prevention of Postsurgical Adhesions", diZerega, Pregnancy Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bldg. 18, Rm. 101, Bethesda, MD 20205.
"Ibuprofen Inhibition of Postsurgical Adhesion Formation: A Time and Dose Response Biochemical Evaluation in Rabbits", Nishimura, Nakamura, and diZerega, Journal of Surgical Research 36, 115-124, Feb., 1984.
"Prevention of Postoperative Adhesions in Rabbits with Ibuprofen, A Nonsteroidal Anti-Inflammatory Agent", Siegler et al., Fertility and Sterility 34, No. 1, pp. 46-49, Jul., 1980.
"Prevention of Postoperative Peritoneal Adhesions with Ibuprofen", Bateman et al., Fertility and Sterility 38, No. 1, pp. 107-108, Jul., 1982.
"Oxyphenbutazone--Anti-Inflammatory Agent--in Prevention of Peritoneal Adhesions", Kapur et al., Arch Surg 98, pp. 301-302, Mar., 1969.
"The Use of Ibuprofen and Dexamethasone in the Prevention of Postoperative Adhesion Formation", O'Brien, Obstetrics & Gynecology 60, No. 3, pp. 373-378, Sep., 1982.
"Biochemical Evaluation of Postsurgical Wound Repair: Prevention of Intraperitoneal Adhesion Formation with Ibuprofen", Nishimura et al., Journal of Surgical Research 34, pp. 219-226, 1983.
"The Carrier Potential of Liposomes in Biology and Medicine", New England Journal of Medicine, vol. 295, pp. 704-710 and pp. 765-770, Sep. 23 and 30, 1976.
diZerega Gere S.
Johns Douglas B.
Richer LeRoy L.
Shalaby Shalaby W.
Sheffield Warren D.
Ethicon Inc.
Nutter Nathan M.
LandOfFree
Method for inhibiting post-surgical adhesion formation by the to does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for inhibiting post-surgical adhesion formation by the to, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for inhibiting post-surgical adhesion formation by the to will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1125814