Method for inhibiting monoamine oxidase-A and treating depressio

Details Method for inhibiting monoamine oxidase-A and treating depressio Method for inhibiting monoamine oxidase-A and treating depressio

1985-02-25

1986-11-18

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549 27, A61K 3139

Patent

active

046236562

ABSTRACT:
3-N-methylcarbamoylthioxanthen-9-one 10,10-dioxide of formula (I) ##STR1## is an inhibitor of monoamine oxidase-A, and is therefore useful in the prophylaxis and treatment of certain mental disorders such as depression.

REFERENCES:
patent: 3310553 (1967-03-01), Bloom et al.
patent: 3642997 (1972-02-01), Shen et al.
patent: 4177257 (1979-12-01), Hodson et al.
D. Sheehan, J. Clin. Psychiatry 45:7, (1984), pp. 29-36.

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