Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1989-02-09
1991-05-14
Lee, Lester L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514 7, 514 19, 514 89, 514 92, 514 94, 514171, 514212, 514218, 514312, 514338, 514343, 514409, 514422, 514423, 514616, 514693, A61K 3700
Patent
active
050156330
ABSTRACT:
A method is provided for inhibiting loss of cognitive function, including memory, which may or may not be associated with Alzhemier's disease, in a mammalian species by administering an ACE inhibitor, which is a phosphonate substituted amino or imino acid or salt, such as SQ 29,852 over a prolonged period of treatment.
REFERENCES:
patent: 4452790 (1984-06-01), Karanewky
Sudilovsky et al., "Captopril Delays Extinction of Conditional Avoidance Response in the Rat", Poster Presentation 14th Congress of the Collegium Internationale Neuro-Psychopharmacologicum, Florence Italy, Jun. 1984.
Melo, J. C. et al., J. Pharmacol., 193:1-9 (1975).
Morgan, J. M. et al., Science, 196:87-89 (1977).
Koller, M. et al., Neuroscience Letters, 14:71-75 (1979).
Evered, M. D. Eurp. J. Pharmacol., 68:443-449 (1980).
Marson, O. et al., Brazil, J. Med. Biol. Res., 14:73-76 (1981).
Arregui, A et al., J. Neurochem., 103:1490-1492 (1982).
Scholkens, B. A. et al., Clin. Exper. Hyper.-Theor. Pract., A5;1301-1317 (1983).
Mann, J. F. E. et al. Clin. Sci., 56:585-589 (1979).
Vollmer, R. R. et al., Europ. J. Pharmacol., 45:117-125 (1977).
"The Effects of Antihypertensive Therapy on the Quality of Life" by S. H. Croog et al. New England Journal of Medicine, 314:1657-1664 (Jun. 26), 1986.
"Angiotensin Converting Enzyme Inhibitors: Animal Experiments Suggest a New Pharmacological Treatment for Alcohol Abuse in Humans" by G. Spinosa et al., Alcoholism: Clinical and Experimental Research, vol. 12, No. 1, Jan./Feb. 1988, pp. 65-70.
"Alcohol Satiety, Hypertension and the Renin-Angiotensin System" by L. A. Grupp, Medical Hypothese (1987) 24, 11-19 (Longman Group UK Ltd. 1987).
E. R. Squibb & Sons Inc.
Lee Lester L.
Rodney Burton
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