Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1998-02-24
1999-12-21
Ulm, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514866, 530399, 530402, A61K 3827, C07K 1461
Patent
active
060049316
ABSTRACT:
Human growth hormone variants are disclosed having enhanced affinity for the growth hormone receptor. Also disclosed are human growth hormone variants conjugated to one or more chemical groups, such as poly(ethylene glycol), which is believed to prolong the in vivo half-life of the variants.
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Clark Ross G.
Cunningham Brian C.
Fuh Germaine G.
Olson Kenneth
Wells James A.
Genentech Inc.
Saoud Christine
Ulm John
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