Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1994-08-08
1996-01-02
Robinson, Allen J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514423, 514561, 514563, A61K 3119, A61K 3140, A61K 31195
Patent
active
054809096
ABSTRACT:
Certain incidents in mammals trigger the generation of free-radicals which are associated with cell death. Animals experiencing such medical incidents are dosed with pyruvate salts or esters in an amount of 5 to 20 weight percent of the total carbohydrate intake. The dosage of pyruvate may be provided to the animal before the medical incident, during the medical incident and after the medical incident. In addition to the known property in pyruvate for scavenging free-radicals, this disclosure points out the unexpected effectiveness of pyruvate as an inhibitor of free-radical generation.
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Keck Harry B.
Robinson Allen J.
University of Pittsburgh Medical Center
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