Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1990-01-08
1992-04-07
Moezie, F. T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 12, 514 21, 424559, A61K 3724, A61K 3702
Patent
active
051028689
ABSTRACT:
A method is provided for inhibiting the maturation of follicles in the ovary of a femal mammal comprising administering to the ovary of the mammal an effective amount of activin. This method is particularly effective in treating polycystic ovarian disease.
REFERENCES:
patent: 4734398 (1988-03-01), di Zerega
patent: 4764502 (1988-08-01), di Zerega
patent: 4798885 (1989-01-01), Mason
patent: 4864019 (1989-09-01), Vale et al.
patent: 4912201 (1990-03-01), Di Zerega
Tsafriri et al., Endocrin, 125:1857-1862 (1989).
Hsueh et al., PNAS U.S.A., 84:5082-5086 (1987).
de Kretser & Robertson, Biol. of Reprod., 40:33-47 (1989).
Ignotz & Massague, J. Biol. Chem., 261:4337-4345 (1986).
Adashi & Resnick, Endocrinology, 119:1879-1881 (1986).
Feng et al., J. Biol. Chem., 261:14167-14170 (1986).
Ying et al., BBRC, 136:969-975 (1986).
Hutchinson et al., BBRC, 146:1405-1412 (1987).
Mondschein et al., Endocrinology, 123:1970-1976 (1988).
Carson et al., J. Reprod. Fert., 85:735-746 (1989).
Gonzales-Manchon & Vale, Endocrinology, 125:1666-1672 (1989).
Baird et al., Ann. N.Y. Acad. Sci, 541:153-161 (1988).
De Jong, Physiol. Rev., 68(2):555-607 (1988).
Sheth & Moodbidri, Adv. Contracept., 2:131-139 (1986).
Findlay, Fertil. Steril., 46:770-783 (1986).
Baker et al., Clin. Reprod. & Fertil, 2:161-174 (1983).
Bremner et al., J. Clin. Invest., 68:1044-1052 (1981).
Lee & Gibson, Aust. J. Biol. Sci., 38:115-120 (1985).
McLachlan et al., Fertil. Steril., 48:1001-1005 (1987).
Cummins et al., J. Reprod. Fert., 77:365-372 (1986).
Henderson et al., J. Endocrin., 102:305-309 (1984).
Forage et al., J. Endocrin., 114:R1-R4 (1987).
Al-Obaidi et al., J. Reprod. Fert., 81:403-414 (1987).
Rivier & Vale, Endocrinology, 125:152-157 (1989).
Franchimont et al., Rev. for Gynecol. Obst., 83:607-611 (1988).
Woodruff et al., Science, 239:1296-1299 (1988).
Hasegawa et al., in "Inhibin: Non-Steroidal Regulation of FSH Secretion", ed. Burger et al., 42:119-133 (N.Y. Raven Press, 1987).
Woodruff et al., in "Growth Factors and the Ovary", Ed. Hirshfield, 291-295 (N.Y.: Plenum Press, 1989).
McLachlan et al., Lancet, 1:1233-1234 (1986).
Tsonis et al., J. Clin. Endocrin. Metab., 66:915-921 (1988).
Buckler et al., J. Endocrin, 122:279-285 (1989).
Tsuchiya et al., Fertil. Steril., 52:88-94 (1989).
Lefevre et al., Fertil., Steril., 46:325-327 (1986).
Tanabe et al., J. Clin. Endocrin. Metab., 57:24-31 (1983).
Yen & Jaffe, eds., Reproductive Endocrinology, Ed. 2, (Saunders, Philadelphia, 1986), p. 441.
Buckler et al., J. Clin. Endocrin. Metab., 66:798-803 (1988).
DiZerega, Nature 323:300 (1986).
Ono et al., Am. J. Obstet. Gynecol., 154(4):709-716 (1986).
Di Zerega et al., J. Steroid Biochem., 27375-383 (1987).
DiZerega et al., Meiotic Inhibiton: Molecular Control of Meiosis, pp. 201-226 (1988).
Tonetta & DiZerega, Endocr. Rev., 10:205-227 (1989).
Mather Jennie P.
Woodruff Teresa K.
Genentech Inc.
Hasak Janet E.
Moezie F. T.
LandOfFree
Method for inhibiting follicular maturation does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for inhibiting follicular maturation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for inhibiting follicular maturation will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1895312