Method for inhibiting clot formation

Surgery: kinesitherapy – Kinesitherapy – Ultrasonic

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12866003, A61B 1722

Patent

active

056204094

ABSTRACT:
The present invention is directed to inhibition of blood clot formation in a first segment of a blood vessel. Inhibition is effected in the first segment by exposing a second segment of the blood vessel to ultrasound. The second segment either contains the upstream region of the first segment or is upstream from this upstream region. A method for preventing a clot-induced event in a patient is also provided.

REFERENCES:
patent: 4227407 (1980-10-01), Drost
Ernst et al., "Ability of high-intensity ultrasound to ablate human atherosclerotic plaques and minimize debris size," Am. J. Cardiol. 68:242-246 (1991).
Francis et al., "Enhancement of fibrinolysis in vitro by ultrasound," J. Clin. Invest. 90:2063-2068 (1992).
Blinc et al., "Characterization of ultrasound-potentiated fibrinolysis in vitro," Blood 81:2636-2643 (1993).
Harpaz et al., "Ultrasound accelerates urokinase-induced thrombosis and reperfusion," American Heart Journal 127:1211-1219 (1994).

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