Method for inhibiting blood-platelet aggregration with .beta.-na

Details Method for inhibiting blood-platelet aggregration with .beta.-na Method for inhibiting blood-platelet aggregration with .beta.-na

1994-06-30

1996-06-04

Weddington, Kevin E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

N-c doai

514590, 514645, 514646, A61K 3127, A61K 31175, A61K 3113, A61K 31135

Patent

active

055233228

ABSTRACT:
A method of inhibiting blood-platelet aggregation in warm-blooded animals comprising administering to warm-blooded animals a blood-platelet aggregation inhibiting effective amount of a compound selected from the group consisting of a compound of the formula ##STR1## wherein R is selected from the group consisting of --NH--CO--NH.sub.2, --NH--CO--CH.sub.3, --OH and their non-toxic, pharmaceutically acceptable acid addition salts.

REFERENCES:
Bressolle et al., "Pharmacokinetics of naftazone in dogs", Framaco, Ed. Prat, (1985). vol. 40, No. 6, pp. 187-198. (enclosed abstract).
La Gazette Medicale, Ploin, Michel., vol. (20) Mar. 27, 1993 p. 38.
Agressologie, vol. (12), pp. 25-30, Laborit et al., "Effects de la mono-semicarbazone de la .beta.-naphtoquinone hemorragique" (1971).

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