Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Patent
1994-01-10
1996-04-09
Gitomer, Ralph J.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
435 19, 435 20, 435184, C12Q 100, C12Q 146
Patent
active
055060978
ABSTRACT:
A method of inhibiting the function of .beta.-protein, particularly enzymatic activity, such as esterase (cholinesterase) or proteinase activity, is to contact .beta.-protein with a compound which inhibits such enzymatic activity. Examples of such inhibitors are para-amidinophenylmethanesulfonyl fluoride and Ebelactone A, which inhibit the esterase activity of amyloid precursor protein to a greater extent than the esterase activity of acetylcholinesterase.
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Kayyali Usamah
Potter Huntington
Gitomer Ralph J.
President and Fellows of Harvard College
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