Method for inhibiting aromatase

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514399, A61K 3141, A61K 31415

Patent

active

052867374

ABSTRACT:
This invention provides a method of inhibiting aromatase and treating of estrogen-dependent diseases in a patient by administering azole derivatives as nonsteroidal inhibitors. The azole derivative has the formula ##STR1## where R.sub.1 a is hydrogen or a (C.sub.1 -C.sub.5) alkyl; R.sub.2 is a hydrogen or a (C.sub.1 -C.sub.5) alkyl; R.sub.3 is any of a halogen, a (C.sub.1 -C.sub.5)alkyl, a haloalkyl, a phenyl, a cyano, or nitro; n is 0 to 5; and Y is a nitrogen atom or CH.

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