Method for inhibiting activation of the human A3 adenosine recep

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514294, 514359, 514461, A61K 3144, A61K 3141, A61K 3134

Patent

active

057804818

ABSTRACT:
The invention is a method for inhibiting activation of the human A3 adenosine receptor with adenosine, by treating the receptor a compound of the formula ##STR1## to treat asthma.

REFERENCES:
Salvatore et al., Proc. Natl. Acad. Sci. USA, "Molecular cloning and characterization of the human A3 adenosine receptor", vol. 90, pp. 10365-10369 (1993).
Katritzky et al., Croatica Chemica Acta, "Cycloaddition Reaction Involving Two Heterocyclic Rings. Preparation of Novel Triazolonaphthyridine Ring Systems", vol 59 (1), pp. 27-32 (1986).

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