Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound having a 1-thia-4-aza-bicyclo
Patent
1994-04-04
1999-03-16
Martinell, James
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound having a 1-thia-4-aza-bicyclo
435 691, 4352523, 43525233, 43525235, 4352543, 43525411, 4353201, 4352545, 536 232, C12P 3700, C12N 1531
Patent
active
058828796
ABSTRACT:
Novel methods and compositions are provided for the enhanced production of .beta.-lactam antibiotics. The process is exemplified by the production of penicillin. In addition, the P. chrysogenum and A. chrysogenum .delta.-(L-.alpha.-aminoadipyl)-L-cysteinyl-D-valine synthetase genes have been isolated and sequenced. Also methods are provided for the production of .delta.-(L-.alpha.-aminoadipyl)-L-cysteinyl-D-valine synthetase using recombined DNA techniques.
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Barredo Jose Luis
Diez Garcia Bruno
Gutierez Santiago
Martin Juan Francisco
Montenegro Prieto Eduardo
Gist-brocades, N.V.
Martinell James
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