Method for inducing HIV neutralizing antibodies using an interna

Drug – bio-affecting and body treating compositions – Lymphokine

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424 858, 530388, 530812, 514 21, 514885, 436547, A61K 3900, A61K 3942, A61K 4502, G01N 3353

Patent

active

049082035

ABSTRACT:
The present invention contemplates a method for inducing a HIV neutralizing immune response using an OKT4A antibody molecule homolog as an immunogen. Vaccines for practicing an immunization method of this invention are also described.

REFERENCES:
Chanh et al, "Monoclonal Anti-Idiotypic Antibody Mimics the CD4 Receptor and Binds Human Immunodeficiency Virus", Proc. Natl Acad Sci, USA, vol. 84, pp. 3891-3895, Jun. 1987.
Zhou et al, "Mouse Monoclonal Anti-Anti-CD.sub.4 Antibodies Recognize Human Immuno-Deficiency Virus Antigens", FASEB, 46:1352 (1987).
Chanh et al, "Anti-Idiotypic Antibodies Against OKTYA Bind to Human Immuno-Deficiency Virus", FASEB, 46:1352 (1987).

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