Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-09-07
1992-02-11
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142355, 5142378, 5142388, 5142395, A61K 31535
Patent
active
050876260
ABSTRACT:
A method for increasing the weight gain and/or improving the feed utilization of efficiency of livestock which comprises administering to livestock in need thereof an effective amount of a compound of formula (XXII): ##STR1## or a pharmaceutically acceptable salt thereof, wherein R.sup.1Z is hydrogen, halogen, or trifluoromethyl; R.sup.2Z is hydrogen or halogen; R.sup.3Z is hydrogen or methyl; R.sup.4Z is --O(CH.sub.2).sup.6 CO.sub.2 H or an ester or amide thereof, O(CH.sub.2).sup..epsilon. M.sup.4 or --CO.sub.2 H or an ester or amide thereof, wherein .delta. is an integer from 1 to 6, .epsilon. is an integer from 2 to 7, and M.sup.4 is hydroxy, alkoxy of 1 to 6 carbon atoms or ##STR2## wherein R.sup.6Z and R.sup.7Z are each hydrogen or alkyl of 1 to 6 carbons or ##STR3## is a 5- or 6-membered ring; R.sup.5Z is alkyl of 1 to 6 carbon atoms; alkyl of 1 to 6 carbon atoms substituted by carboxy or an ester or amide thereof; or phenyl unsubstituted or substituted by alkyl of 1 to 6 carbon atoms, halogen, lower alkoxy or trifluoromethyl R.sup.8Z is hydrogen or alkyl of 1 to 6 carbon atoms or R.sup.8Z together with R.sup.5Z is a carbocyclic ring.
REFERENCES:
patent: 4404222 (1983-09-01), Baker et al.
patent: 4596800 (1986-06-01), Ainsworth et al.
patent: 4607033 (1986-08-01), Cantello
Beecham Group p.l.c
Waddell Frederick E.
Weddington K.
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