Method for increasing the proportion of a crystalline organic co

Details Method for increasing the proportion of a crystalline organic co Method for increasing the proportion of a crystalline organic co

1992-03-20

1994-08-09

Langel, Wayne

Chemistry: physical processes

Physical processes

241 16, 241 27, 514160, 514404, 514420, 514568, 514570, 514625, B01J 800

Patent

active

053362713

ABSTRACT:
A method for increasing the proportion of a crystalline organic compound which remains amorphous and suppressing recrystallization in which a crystalline organic compound and a hydrophilic polymer substance are fixed onto a surface of core particles by means of impacts applied in a high velocity gas stream. The solubility and stability of the resulting composite product, such as a drug for internal use, can be improved.

REFERENCES:
patent: 3688991 (1972-09-01), Andrews
patent: 3713593 (1973-01-01), Morris et al.
patent: 4298399 (1981-11-01), Formica et al.

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