Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1995-04-19
1997-07-15
Guzo, David
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
43525422, C12P 744, C12N 116
Patent
active
056482477
ABSTRACT:
The omega-hydroxylase activity in the yeast Candida tropicalis is increased by amplification of the P450ALK and P450RED genes. The specific productivity (grams of dicarboxylic acid/liter/hr) of substantially pure alpha, omega-dicarboxylic acids is increased by culturing C. tropicalis strains having amplified P450ALK and P450RED genes.
REFERENCES:
patent: 3975234 (1976-08-01), Hitzman
patent: 4339536 (1982-07-01), Kato et al.
patent: 4474882 (1984-10-01), Kunishige et al.
Liskay et al., 1987, Genetics, vol. 115: 161-167.
Okazaki et al. Gene 57:37-44 (1987).
Okazaki et al. Biochem 83:1232 (1986).
Sanglard et al. Gene 76:121 (1989).
Sanglard "FEBS lett." 256:128 (1989).
Sanglard "Experientia" 49: 1983, #Gen 418 (1988).
Loper "Genetics" 113:Suppl. No. 1, P+2, 514 #2.18 (1986).
Loper et al. U.S. Envir. Prot. Agency Res Dev 1984. Abstract only.
ATCC catalogue 7th Ed. 1987 (Fergi +Yeaki) p. 80.
Kelly et al. Mol. Cell Biol Jan 1987: 199.
Gillum et al. Mol. Gen Genet 198:179 (1984).
Strommae et al. J. Bact Jan. 1986:197.
Aitchardin et al. Chem Abstr. 77(23): No. 149584A (1971).
Gaillardin et al. Chem Abstr. 77(23):No. 149584A (1971).
Wataabe et al. Chem Abstr. 70(15):No. 65372n (1968).
Small et al. J. Cell Biol 105:247 (1987).
Acta Microbiol. Sim. 21:88-95 (1981), Abstract only.
Agr. Biol. Chem. 35 2033-2042 (1971) Shiio et al., "Microbial Production of Long-Chain Dicarboxylic Acids from n-Alkanes".
Lawrence et al. (eds) Flavors and Fragrances: A World Perspective (1988) Okino et al., "Production of Macrocyclic Musk Compounds . . . from n-Alkanes".
Aliphatic Hydrocarbons in Biotechnology, vol. 6a, Verlag Chemie, Weinheim (1984) Buehler et al.
Gilewicz et al., Can. J. Microbiol., 25 pp. 201-206 (1979), "Hydroxylase regulation in Candida tropicalis grown on alkanes".
Sanglard & Loper, Gene 76, 121-136 (1989), "Characterization of the alkane-inducible cytochrome P450 (P450 alk) gene from the yeast Candida tropicalis".
Kemp et al., Appl. Microbiol. and Biotechnol, 29 pp. 370-374 (1988) "Inducible long chain alcohol oxidase from alkane-grown Candida tropicalis".
J. Biochem., 102 225-234 (1987) Vamecq et al., "Interactions between the .omega.-and .beta.-Oxidations of Fatty Acids".
Agr. Biol. Chem., 49 1821-1828 (1985), Ueda et al. "Peroxisomal Localization of Enzymes Related to Fatty Acid .beta.-Oxidation in . . . Candida tropicalis".
Eirich L. Dudley
Picataggio Stephen
Rohrer Tracy
Drach John E.
Guzo David
Henkel Corporation
Jaeschke Wayne C.
Schwartzmann Robert
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