Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1980-11-12
1982-09-14
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
2601125R, A61K 3700, C07C10352
Patent
active
043495443
ABSTRACT:
The use of long-acting oxytocin analogs, characterized chemically by replacement of the disulfide bridge by a thioether bridge, in safely increasing the milk products in mammals is disclosed. Of particular importance in the use of these compounds is the safety factor, that is, the absence of dangerous side effects at dosage levels required for increasing lactation. An increase in milk production can be accomplished with one or, at most, two single injections.
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patent: 3752799 (1973-08-01), Jost et al.
patent: 4237119 (1980-12-01), Cort et al.
Porchiana, et al., Experimentia (1964) 24, 570-571.
Kobayashi, et al., Bull. Chem. Soc. Japan, 42, 3491-3495 (1969).
Berde, Molecular Aspects 1968, 53-65.
Chem. Abstr. 74, 1971 10016b.
Barth Tomislav
Cort Joseph H.
Jost Karel
Veznik Zdenek
Ceskoslovenska akademie ved
Phillips Delbert R.
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