Method for increasing the bioavailability of glycopyrrolate

Details Method for increasing the bioavailability of glycopyrrolate Method for increasing the bioavailability of glycopyrrolate

2006-08-15

2006-08-15

Spivack, Phyllis G. (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

Reexamination Certificate

active

07091236

ABSTRACT:
The invention relates to a method of increasing the bioavailability of glycopyrrolate by administration of a therapeutically effective amount of glycopyrrolate without food.

REFERENCES:
patent: 6407128 (2002-06-01), Scaife et al.
patent: 6455557 (2002-09-01), Pellegrini et al.
patent: WO 01/08681 (2001-02-01), None
Ali-Melkkila er al, “Glycopyrrolate: pharmacokinetics and some pharmacodynamic findings,”Acta Anaesthesiol. Scand., 33: 513-517 (1989).
Ali-Melkkila et al., “Pharmacokinetics and related pharmacodynamics of anticholinergic drugs,”Acta Anasthesiol. Scand., 37: 633-642 (1993).
Chen, “Troglitazone: An antidiabetic agent,”Am J. of Health-Syst. Pharm., 55:905-925 (1998).
Evans, “Influence of Dietary Components on the Gastrointestinal Metabolism and Transport of Drugs,”Therapeutic Drug Monitoring, 22: 131-136 (2000).
Greene et al., “Clinical Pharmacokinetics of Nefazodone,”Clin. Pharmacokinet., 33(4): 260-275 (1997).
Gillen et al., “Problems related to acid rebound and tachyphylaxis,”Best Pract.&Res. Clin. Gastroenterology, 15(3): 487-495 (2001).
Kirk, “Significant Drug-Nutrient Interactions,”Amer. Fam. Phys., 51(5): 1175-1182 (1995).
Loi et al., “Clinical Pharmacokinetics of Troglitazaone,”Clin. Pharmacokinet., 37(2):91-104 (1999).
Martinez et al., “A Mechanistic Approach to Understanding the Factors Affecting Drug Absorption: A Review of Fundamentals,”J. Clin. Pharmacol., 42: 620-643 (2002).
Pelkonen et al., “In vitro prediction of gastrointestinal absorption and bioavailability: and experts' meeting report,”Eur. J. Clin. Pharmacol., 57: 621-629 (2001).
Rautakorpi et al., “Pharmacokinetics and Oral Bioavailability of Glycopryrrolate in Children,”Pharmacology&Toxicology, 83: 132-134 (1998).
Rautakorpi et al., “Pharmacokinetics of Glycopyrrolate in Children,”J. Clin. Anesth., 6: 217-220 (1994).
Singh, “Effects of Food on Clinical Pharmacokinetics,”Clin. Pharmacokinet., 37(3): 213-255 (1999).
Temple et al., “Rifapentine: Its Role in the Treatment of Tuberculosis,”The Annals of Pharmacotherapy,33: 1203-1210 (1999).
Toothaker et al., “The Effect of Food on Drug Bioavailability,”Ann. Rev. Pharmacol. Toxical., 20: 173-199 (1980).
van Leerdam et al. “The role of acid suppressants in upper gastrointestinal ulcer bleeding”,Best Pract.&Res. Clin. Gastroenterology, 15(3): 463-475 (2001).
Walter-Sack et al., “Influence of Diet and Nutritional Status on Drug Metabolism,”Clin. Pharmacokinet., 31(1): 47-64 (1996).
Welling, “Interactions Affecting Drug Absorption,”Clin. Pharmacokinet., 9: 404-434 (1984).

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