Method for increasing placental blood flow

Details Method for increasing placental blood flow Method for increasing placental blood flow

1996-04-24

1999-03-30

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 8, 514 21, 514822, 514929, A61K 3814, A61K 3836

Patent

active

058889647

ABSTRACT:
A method for increasing the placental blood flow, which comprises administering a human-originated antithrombin-III. The human-originated antithrombin-III increases the placental blood flow in mammals and particularly improves intrauterine growth retardation caused by a decreased blood flow. The method is highly safe to the mother and fetus, since it uses human-originated AT-III as an active ingredient, thereby enabling effective and safe treatment of intrauterine growth retardation (IUGR) and the like.

REFERENCES:
Shinyama et al., Jap. J. of Pharm. 68th Annual Mtg of Japanese Pharmacological Society, Nagoya Japan Mar. 25-28, 1995 vol. 67 Apr. 11, 1995 p. 278 P No. P3 126.
JP 07316072 Abstract in English.
Moe, Anticoag. Ther. & Perinatal Death vol. 59 No. 4 Apr. 1982 pp. 481-483.
Valcamonico et al, J. Perinat. Med. vol. 21 (May 1993) pp. 235-240.

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