Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing
Patent
1995-06-07
1999-03-30
Chambers, Jasemine C.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
424520, 424577, 424 933, 424 937, 424 9321, 435325, 435326, 435366, 435372, 4351723, 435 691, 514 44, A61K 3528, A61K 3514, C12N 502, C12N 508
Patent
active
058884998
ABSTRACT:
A suspension comprising human neutrophil precursor cells, wherein the cellular component is comprised of at least about 16% human myeloblasts and promyeclocytes, which have been derived from neutrophis progenitor cells obtained from peripheral blood, bone marrow or cord blood, and less than about 5% colony forming units (CFU) of at least about 50 cells is provided. An alternative suspension comprising human neutrophil precursor cells, wherein the cellular component is comprised of at least about 16% CD15+CD11b- cells and less than about 5% colony forming units (CFU) of at least about 50 cells also is provided, wherein at least about 60% of the CD15+CD11b- cells are myeloblasts and promyelocytes. The suspensions of the invention are useful in methods for increasing neutrophil populations in a patient having a reduced populations of neutrophils.
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Bender James G.
Maples Phillip B.
Smith Stephen
Unverzagt Kristen L.
Van Epps Dennis E.
Chambers Jasemine C.
Nexell Therapeutics Inc.
Schmuck Jill D.
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