Method for increasing hydrophilicity of fluorescent label...

Details Method for increasing hydrophilicity of fluorescent label... Method for increasing hydrophilicity of fluorescent label...

2007-04-03

2007-04-03

Ceperley, Mary E. (Department: 1641)

Chemistry: analytical and immunological testing

Involving producing or treating antigen or hapten

Producing labeled antigens

C435S006120, C435S040500, C436S172000, C530S391500, C530S402000, C530S409000, C544S180000, C544S229000

Reexamination Certificate

active

10482057

ABSTRACT:
A fluorescent label compound of formulawhere Z is a reactive group that can be used for covalent coupling of the fluorescent label compound to other molecule. Either the fluorophore is a dipyrrometheneboron difluoride dye and Y is a water-solubilizing moiety, or Y is —CH2CH2SO3−X+where X+is a cation. The use of the compounds in bianalytical assays and cytological or histological staining methods, and a method for increasing the hydrophilicity of fluorescent compounds, are also disclosed.

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