Method for increasing coronary blood flow in mammals

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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42424856, A61K 31445, A61K 31535

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active

041637909

ABSTRACT:
Compounds of the following general formula are useful for increasing coronary blood flow in mammals: ##STR1## wherein R is hydrogen, acetyl, p-fluorobenzoylpropyl, carbamoyl, N-methylcarbamoyl, N,N-dimethylcarbamoyl, phenylcarbamoyl, or N-(.omega.-morpholinoethyl)carbamoyl; R.sup.1 is hydrogen; R.sup.2 is hydrogen or hydroxy; or R.sup.1 and R.sup.2 taken together form a second bond between the carbon atoms bearing R.sup.1 and R.sup.2 ; R.sup.3 is hydrogen or fluorine and pharmaceutically acceptable acid addition salts thereof.

REFERENCES:
patent: 3806526 (1974-04-01), Carr et al.
patent: 3852455 (1974-12-01), Carr
patent: 3922276 (1975-11-01), Duncan et al.
patent: 3931197 (1976-01-01), Carr et al.
patent: 3946022 (1976-03-01), Carr et al.
patent: 3956296 (1976-05-01), Duncan et al.
Chem. Abst. 72, 100535(h), 1970-Duncan et al.

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