Method for incorporating substances into protein microspheres

Details Method for incorporating substances into protein microspheres Method for incorporating substances into protein microspheres

1972-11-06

1976-02-10

Lovering, Richard D.

Compositions

Preservative agents

Anti-corrosion

427 3, 2523011R, 2523011S, 252408, 264 5, 424 1, 424 2, 424 7, 424 19, 424 36, 424178, B01j 1302, B44d 102

Patent

active

039376680

ABSTRACT:
The subject matter of this invention is a process for solid albumin particles so that such spheric particles may act as a carrier for radioactivity, drugs, insecticides, dyes, metal salts, etc. In order to prepare such spheric particles, the substance to be incorporated therein is transformed into a precipitate. This precipitate is then mixed with an aqueous solution of albumin. The mixture thus prepared is then injected into cotton seed oil while stirring so as to obtain a fine dispersion of the albumin droplets and the precipitate in the oil, then the mixture is heated above 100.degree.C to evaporate water and to form spheric albumin particles having the precipitate encapsulated therein.

REFERENCES:
patent: 2911338 (1959-11-01), Tabern et al.
patent: 3137630 (1964-06-01), Hecker et al.
patent: 3137631 (1964-06-01), Soloway
patent: 3663685 (1972-05-01), Evans

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