Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-07-08
2000-12-26
Guzo, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 691, 435471, 435476, 435488, 4353201, 435489, 43525233, 435189, 435193, 435195, C12Q 168, C12N 1570, C12N 1563, C12N 910, C12N 914
Patent
active
061657182
ABSTRACT:
A method for in vivo production of a library in cells comprising a multitude of mutated genetic elements, wherein an error-prone polymerase is used in each ancestral cell to replicate all or a part of a genetic element independently of the host chromosomal replication machinery. The genetic element comprises
REFERENCES:
James E. Bailey, Science, vol. 252, pp. 1668-1675, Jun. 21, 1991.
Borchert Torben Vedel
Ehrlich Stanislas Dusko
Gregg Valeta
Guzo David
Lambiris Elias J.
Novo Nordisk A/S Novo Alle
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