Method for in vivo chemically triggered disintegration of medica

Details Method for in vivo chemically triggered disintegration of medica Method for in vivo chemically triggered disintegration of medica

1996-03-18

1998-10-13

Coggins, Wynn Wood

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

424426, 424 781, A61M 532, A61M 2500

Patent

active

058206086

ABSTRACT:
The present invention provides medical devices comprised of ionically crosslinked polymer, especially, stents, catheter or cannula components, plugs, and constrictors. The medical devices of the present invention are prepared by treatment of ionically crosslinkable polymer compositions with crosslinking ion compositions to provide ionically crosslinked materials.
An important aspect of the present invention is that these medical devices can be disintegrated in-vivo at a desired time through the exposure of the medical device to a chemical trigger which generally is described as an agent that acts to displace the crosslinking ion in the ionically crosslinked material through binding or simple replacement with a non-crosslinking ion.

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