Method for improving ventilation during sleep and treating sleep

Details Method for improving ventilation during sleep and treating sleep Method for improving ventilation during sleep and treating sleep

1991-02-15

1992-08-18

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

A61K 31195

Patent

active

051400456

ABSTRACT:
A method for improving ventilation during sleep and treating sleep-related ventilation abnormalities in an infant. To this end, the present invention provides a method of using branched-chain amino acids as an effective therapy for apnea of prematurity. The branched-chain amino acid composition can be administered either parenterally or enterally, and can be administered alone or in combination with other nutrients.

REFERENCES:
patent: 4209531 (1980-06-01), Berry
patent: 5017616 (1991-05-01), Askanazi
Ghadimi et al., Total Parenteral Nutrition for Preventing and Treatment of RDS, p. 573 (1973).
J. Takala et al., Changes in Respiratory Control Induced by Amino Acid Infusions, Critical Care Medicine, vol. 16, No. 5, (May 1988) pp. 465-469.
The Merck Manual, 14th edition (1982) p. 1763.

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