Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Patent
1985-09-06
1989-04-18
Tarcza, John Edward
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
4351722, 43524027, 424 858, 935 93, 935108, 530387, 530396, 530413, C12P 2100, C12N 1500, C12N 500, A61K 3900
Patent
active
048227340
ABSTRACT:
Methods are disclosed for improving the efficiency of elicitation of monoclonal antibodies to glycoprotein antigens and tumor-associated antigens, and for inducing the production of IgG class monoclonal antibodies, in particular the IgG.sub.3 subclass. The methods involve the use of a lectin/extract immunogen to stimulate the production of the desired monoclonal antibodies.
REFERENCES:
patent: 4372945 (1983-02-01), Likhite
patent: 4416866 (1983-11-01), Strand
patent: 4427653 (1984-01-01), Springer
patent: 4487833 (1984-12-01), Donahoe et al.
patent: 4720386 (1988-01-01), McCollester
McMaster et al., European Journal of Immunology 9(6), pp. 426-433 (1979).
Sunderland et al., European Journal of Immunology 9(2) 155-159 (1979).
A. C. Morgan, Jr. and R. A. Reisfeld, Biological Significance of Human Melanoma-Associated Antigens Defined by Xenoantisera, in "Advances in Immunopathology", pp. 299-314, Elsevier North Holland, Inc., 1981.
A. C. Morgan, Jr. et al., "Production and Characterization of Monoclonal Antibody to a Melanoma Specific Glycoprotein", Hybridoma 1:27-35 , 1981.
A. C. Morgan, Jr., Monoclonal Antibodies to Human Melanoma-Associated Antigens: Elicitation and Evaluation with Immunochemically Defined Antigen Preparations, in "Melanoma Antigens and Antibodies", pp. 279-288, Plenum Publ. Corp., 1982.
A. C. Morgan, Jr. et al., "Monoclonal Antibodies to Human Colorectal Tumor-Associated Antigens: Improved Elicitation and Subclass Restriction", Hybridoma 3:233-245, 1984.
G. M. Stuhlmiller et al., "D6.1, A Murine Antimelanoma Monoclonal Antibody from Congenitally Athymic Nude Mice Immunized with Purified Melanoma Tumor-Associated Antigen", Hybridoma 3:333-346, 1984.
C. Kordon-Cardo et al., "Immunopathologic Analysis of a Phase I Trial in Patients with Malignant Melanoma", Fed. Proc. 44:8483, 1985.
Abrams Paul G.
McIntyre Robert
Morgan, Jr. Alton C.
Woodhouse Clive S.
NeoRx Corporation
Tarcza John Edward
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