Method for improving the detection of fluorescence signals...

Details Method for improving the detection of fluorescence signals... Method for improving the detection of fluorescence signals...

2011-01-18

2011-01-18

Porta, David P (Department: 2884)

Radiant energy

Luminophor irradiation

C250S459100

Reexamination Certificate

active

07872243

ABSTRACT:
The invention concerns the use of the fluorescence polarization phenomenon to improve detection of fluorescent signals during a fluorescence resonance energy transfer (FRET). In particular, the invention concerns a method for improving signal
oise ratio in a FRET measurement. The invention also concerns an apparatus for measuring fluorescence following an energy transfer between a donor fluorescent compound and an acceptor fluorescence compound in a measurement medium.

REFERENCES:
patent: 2003/0058442 (2003-03-01), Garab et al.
patent: WO 2006/010839 (2006-02-01), None
patent: WO 2006/010839 (2006-02-01), None
“Quantitative Fluorescence Resonance Energy Transfer Measurements Using Fluorescence Microscopy,” Gerald W. Gordon et al.,Biophysical Journal—May 1998, vol. 74, pp. 2702-2713 (XP-000990953).
“Homo-FRET Microscopy in Living Cells to Measure Monomer-Dimer Transition of GFP-Tagged Proteins,” I. Gautier et al.,Biophysical Journal—Jun. 2001, vol. 80, pp. 3000-3008 (XP-002977865).
“Reliable and Global Measurement of Fluorescence Resonance Energy Transfer Using Fluorescence Microscopes,” Zongping Xia et al., Biophysical Journal—Oct. 2001, vol. 81, pp. 2395-2402 (XP-002328970).
“Fluorescence Resonance Energy Transfers Measurements on Cell Surfaces via Fluorescence Polarization,” Meir Cohen-Kashi et al.,Biophysical Journal—Sep. 2002, vol. 83, pp. 1395-1402 (XP-002328968).
“Detection of Tryptophan to Tryptophan Energy Transfer in Proteins,” Pierre Moens et al.,The Protein Journal, Jan. 2004, vol. 23, No. 1, pp. 79-83 (XP-002328973).
English Abstract of JP 2002/098638 published Apr. 5, 2002.

Affiliated with

Also associated with

Rating

Method for improving the detection of fluorescence signals... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for improving the detection of fluorescence signals..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for improving the detection of fluorescence signals... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2743091