Method for improving intestinal absorption of cephalosporin deri

Details Method for improving intestinal absorption of cephalosporin deri Method for improving intestinal absorption of cephalosporin deri

1982-02-24

1984-08-14

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

A61K 3702

Patent

active

044656688

ABSTRACT:
A method for improving the intestinal absorption of a cephalosporin derivative by bonding an oligopeptide having the general formula (I): ##STR1## wherein X is a hydrogen atom, C.sub.1-15 alkyl group, R.sub.3 CO-- group wherein R.sub.3 is a hydrogen atom or straight or branched chain C.sub.1-15 alkyl group or a protective group easily removable by acid hydrolysis, hydrogenolysis or enzyme existing in a living body;

REFERENCES:
patent: 3925370 (1975-12-01), Wei et al.
patent: 3929781 (1975-12-01), Teller et al.
patent: 4087424 (1978-05-01), Saikawa et al.
patent: 4112090 (1978-09-01), Saikawa et al.
patent: 4162314 (1979-07-01), Gottschlick et al.
patent: 4276288 (1981-06-01), Etschenberg et al.
Wheeler, J. of Med. Chem., vol. 22, No. 6, 657-661 (1979).

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