Method for improving implant fixation

Details Method for improving implant fixation Method for improving implant fixation

1990-05-23

1993-11-02

Isabella, David

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Bone

623 66, A61F 228

Patent

active

052580296

ABSTRACT:
Stress-bearing prostheses for replacement or partial replacement of stress-bearing bone are fixed in place by bony ingrowth by providing a stress-bearing member having a porous region in combination with an osteogenic factor extract or a purified osteogenic inductive protein, optionally in combination with a TGF-beta cofactor, in a pharmaceutically acceptable carrier. The carrier is preferably either a collagen composition or a ceramic.

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Bentz et al., Development and Diseases of Cartilage and Bone Matrix (1987) Alan R. Liss, et al., pp. 137-147.

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