Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues
Patent
1998-10-13
2000-03-28
Brusca, John S.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
435 698, 514 2, A61K 3816, C12P 2104
Patent
active
060433396
ABSTRACT:
The present invention relates to the delivery of biologically active molecules, such as peptides, nucleic acids and therapeutic agents, into the interior of cells by administering to the cells a complex comprising the molecule linked to an importation competent signal peptide. Such delivery can be utilized for purposes such as peptide therapy, gene transfer, and antisense therapy.
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Hawiger Jack J.
Lin Yao-Zhong
Brusca John S.
Shuman Jon D
Vanderbilt University
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