Method for immunoassays based on infrared reflection...

Details Method for immunoassays based on infrared reflection... Method for immunoassays based on infrared reflection...

2006-01-24

2006-01-24

Do, Pensee T (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

C436S501000, C435S004000, C435S007100, C435S007400, C435S007920, C435S007930, C435S007940, C435S007950, C422S082050, C422S051000, C422S051000, C422S068100, C422S082010, C250S339120, C250S339060, C250S458100, C250S297000

Reexamination Certificate

active

06989277

ABSTRACT:
This invention relates to a method for immunoassays based on infrared reflection absorption spectroscopy that utilizes proteins such as antigen and antibody that have specific absorptions in infrared absorption spectrum under 1550 cm−1. A chip is made from infrared reflective substrates such as a gold or silver plate, whereon the antibodies or antigens are immobilized by the specific bonding action between metal surfaces of the chip and proteins, and the protein signals are then detected by infrared reflection-absorption and infrared microscopy. Since infrared radiation is capable of interacting with any organic molecules, there is no need to label the samples with fluorescent reagents or nucleic irradiation reagent. This invention thus provides a label-free process that can avoid the inconvenience of labeling common biochemical material for detection in the prior art, thus achieving the purpose of higher speed of detection.

REFERENCES:
patent: 4975581 (1990-12-01), Robinson et al.
patent: 5620856 (1997-04-01), Carlson et al.
patent: 5716854 (1998-02-01), Lofas et al.
patent: 5977545 (1999-11-01), Haar et al.
patent: 6284197 (2001-09-01), Abbott et al.
patent: 6313914 (2001-11-01), Roe
patent: 6699724 (2004-03-01), West et al.

Affiliated with

Also associated with

Rating

Method for immunoassays based on infrared reflection... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for immunoassays based on infrared reflection..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for immunoassays based on infrared reflection... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3553886